Drugs design and Technology
Many modern medications were discovered through animal and human research. Many medications now target the specific disorder. By identifying aberrant biochemical and cellular changes caused by disease, chemicals can be created to prevent or rectify them (by interacting with specific body areas). When a novel chemical shows potential, its structure is tweaked. Optimize site targeting ( selectivity) Stay online ( affinity) Strengthen it ( potency, efficacy, effectiveness) Safety-proof (minimize side effects) Other factors include intestine absorption and stability in body tissues and fluids. These include drug kinetics and drug pharmacokinetics ( drug dynamics). Ideally, the drug is It’s very selective for its target site and has low or no adverse effects (see Overview of Adverse Drug Reactions). Effective: Even for difficult-to-treat illnesses, low doses can be employed. Effective when eaten by mouth (absorbed well): Convenient. Stable in human tissues and fluids; one dose a day i...